Another example of a 'half dose' drug which is available over the counter is Zantac (generic Ranitidine). When I was prescribed it for acid reflux, I did my cautious websearch (as I do

), and found no reports whatsoever of any side effects, so I happily used it for several years.
It is only now, when I have CFS caused by vitamin B12 deficiency, that I learn that the limitation of stomach acid (Losec does this too) restricts the absorption of vitaminB12 from food.
Nowadays I regard all pharmacutical drugs, prescription or otherwise, with
extreme caution.